The effect of retinoic acid on the proportion of insulin cells in the developing chick pancreas


We assessed the potential role of all-trans-retinoic acid on the developing chick pancreas, specifically with regard to the proportions of insulin cells. The endodermal component of the dorsal pancreatic bud of 5-d-old chick embryos was cultured on Matrigel. Retinoic acid (10−6 or 10−5 M) was added to a standard serum-free medium, Ham's F12 containing… (More)
DOI: 10.1290/1071-2690(2000)036<0014:TEORAO>2.0.CO;2


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