The effect of restraint stress on experimental colitis is IFN-gamma independent.

Abstract

Stress, a protective reaction to external threats, may be deleterious if linked to an inflammatory stimulus. Stress may influence intestinal immunity, thereby contributing to the development of colitis. Less severe histological abnormalities and clinical scores were detected in dextran sulphate sodium (DSS)-induced colitis in IFN-gamma(-/-), compared to Wt… (More)
DOI: 10.1016/j.jneuroim.2008.06.008

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