The effect of reduction of propellant mass fraction on the injection profile of metered dose inhalers.


In order to provide an improved understanding of the flow in pressurized-metered dose inhalers (pMDIs), especially monitoring the output temperature and mass flow rate to obtain maximum atomization efficiency from the available energy, a numerical model for a two phases, multi-component compressible flow in a pressurized-metered dose inhaler is presented… (More)
DOI: 10.1016/j.ijpharm.2010.03.003


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