The effect of reduced oxygen tension on platelet formation in vitro.


It is now generally accepted that platelets are formed in the bone marrow from megakaryocytes. This suggestion was first clearly made by Wright (1906), who based his case on embryological and microscopical arguments as well as on considerations of comparative biology. The question was, however, settled when Thiery and Bessis in 1956 produced their beautiful… (More)


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