The effect of ranitidine versus proton pump inhibitors on gastric secretions: a meta‐analysis of randomised control trials

@article{Clark2009TheEO,
  title={The effect of ranitidine versus proton pump inhibitors on gastric secretions: a meta‐analysis of randomised control trials},
  author={K. Clark and L. T. Lam and S. Gibson and D. Currow},
  journal={Anaesthesia},
  year={2009},
  volume={64}
}
  • K. Clark, L. T. Lam, +1 author D. Currow
  • Published 2009
  • Medicine
  • Anaesthesia
  • Aspiration of acid into the lungs is an infrequent but potentially devastating complication of general anaesthesia. Routine practice often includes use of pharmacological agents to reduce gastric volume and increase gastric pH. The aim of this study was to compare the net benefit of proton pump inhibitors with histamine 2 blockers in a meta‐analysis. Electronic databases were searched for trials that compared ranitidine vs proton pump inhibitors in their effect on volume and pH of gastric fluid… CONTINUE READING
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