The effect of raloxifene after discontinuation of long-term alendronate treatment of postmenopausal osteoporosis.

@article{Michalsk2006TheEO,
  title={The effect of raloxifene after discontinuation of long-term alendronate treatment of postmenopausal osteoporosis.},
  author={Dana Michalsk{\'a} and Jan J. {\vS}těp{\'a}n and Bruce R. Basson and Imre J. Pavo},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 3},
  pages={870-7}
}
OBJECTIVE The aim of this study was to compare bone mineral density (BMD) and biochemical markers of bone turnover in patients receiving long-term alendronate therapy who continued alendronate, were switched to raloxifene, or discontinued antiresorptive therapy. DESIGN, PATIENTS, AND INTERVENTIONS Ninety-nine ambulatory women who were diagnosed with postmenopausal osteoporosis and treated with alendronate (10 mg/d) for a mean period of 43 months were randomized to double-blind raloxifene (60… CONTINUE READING

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