The effect of pyrrolizidine alkaloids (Senecio vulgaris) on the liver mixed-funcion oxidase system.

@article{Eastman1980TheEO,
  title={The effect of pyrrolizidine alkaloids (Senecio vulgaris) on the liver mixed-funcion oxidase system.},
  author={D. Eastman and H. J. Segall},
  journal={Toxicology letters},
  year={1980},
  volume={5 6},
  pages={
          369-74
        }
}
  • D. Eastman, H. J. Segall
  • Published 1980
  • Biology, Medicine
  • Toxicology letters
  • A model system to detect the toxicity of pyrrolizidine alkaloids (PAs) was explored. Using the liver S-10 fraction, the effect of PAs on aniline hydroxylase and aminopyrine N-demethylase was examined. PAs were toxic to the aminopyrine N-demethylase enzyme system while exerting no toxicity on the aniline hydroxylase enzyme system. 
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