The effect of pyrimidine nucleosides on adenosine-induced apoptosis in HL-60 cells

Abstract

Among several nucleosides, adenosine is the only one to induce typical apoptotic cell death in human promyelocytic leukemia HL-60 cells. Intracellularly transported adenosine seemed to be required for the induction of apoptosis, since dipyridamole, which inhibits the transport of adenosine, strongly suppressed apoptosis, and 8-phenyltheophylline, a receptor… (More)
DOI: 10.1007/s004320050201

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