The effect of pulsatile human corticotropin-releasing hormone administration on the adrenal insufficiency that follows cure of Cushing's disease.

Abstract

Successful transsphenoidal surgery for Cushing's disease leads to secondary adrenal insufficiency in most patients. This form of transient adrenal insufficiency is thought to result from hypothalamic and pituitary suppression due to the preceding hypercortisolism. Whether the rate-limiting step in the recovery of adrenal function in this setting is the… (More)

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@article{Avgerinos1989TheEO, title={The effect of pulsatile human corticotropin-releasing hormone administration on the adrenal insufficiency that follows cure of Cushing's disease.}, author={Peter C. Avgerinos and Lynette K Nieman and Edward H. Oldfield and Thomas R. Loughlin and K. M. Barnes and Donald L Loriaux and Gordon B. Cutler}, journal={The Journal of clinical endocrinology and metabolism}, year={1989}, volume={68 5}, pages={912-6} }