The effect of proton pump inhibitors on the gastric mucosal microenvironment.


BACKGROUND Proton pump inhibitors (PPIs) are widely applied for acid related disorders, and possess pleiotropic biological functions. The effect of PPIs on the gastric mucosa, neutrophil and Helicobacter pylori (H. pylori) infiltration and glandular atrophy has not been well investigated, particularly the duration of the effects of PPIs. OBJECTIVES To… (More)
DOI: 10.17219/acem/33116