The effect of prostaglandins on the release of arginine vasopressin from the guinea pig hypothalamo-neurohypophyseal complex in organ culture.

@article{Ishikawa1981TheEO,
  title={The effect of prostaglandins on the release of arginine vasopressin from the guinea pig hypothalamo-neurohypophyseal complex in organ culture.},
  author={San‐e Ishikawa and T. Saito and S Yoshida},
  journal={Endocrinology},
  year={1981},
  volume={108 1},
  pages={
          193-8
        }
}
The effect of prostaglandins (PGs) on arginine vasopressin (AVP) release was investigated using the male guinea pig hypothalamo-neurohypophyseal complex (HNC) in organ culture. The explants of HNC were used on the second day in culture. The culture medium containing PGE2 caused an increase in AVP release from the explants during a 10-min incubation period. AVP release was significantly increased at a PGE2 concentration of 2 X 10(-8) M or more. AVP release was increased in a dose-dependent… 
On the failure of prostaglandin synthetase inhibitor indomethacin to affect the osmoregulation of plasma arginine vasopressin in rats.
TLDR
It is concluded that central endogenous PG has no primary role in the control of the osmoregulation of arginine vasopressin secretion under normal physiological conditions.
Role of brain prostaglandins in the control of vasopressin secretion in the conscious rat.
TLDR
It is concluded that brain PGs play a central role in the control of AVP secretion.
Possible roles of prostaglandins in the anteroventral third ventricular region in the hyperosmolality-evoked vasopressin secretion of conscious rats
TLDR
It is concluded that prostaglandins synthesized in and/or near the anteroventral third ventricular region might contribute to the facilitation of vasopressin release in the hyperosmotic state.
Possible participation of prostaglandins generated in the anteroventral third ventricular region in the hypovolemia-induced vasopressin secretion of conscious rats.
TLDR
The results suggest that PGs synthesized in and/or near the AV 3V may be involved in the regulation of AVP release and cardiovascular function in the hypovolemic state.
Effects of prostaglandin E2 and D2 on the release of vasopressin and oxytocin.
The guinea pig hypothalamo-neurohypophyseal complex in organ culture for oxytocin studies.
TLDR
The guinea pig hypothalamo-neurohypophyseal complex was assessed as a possible in vitro model for oxytocin (OT) studies and it was indicated that OT was released from the HNC in constant quantities.
Role of AVP in pressor responses during activation of central TxA2/PGH2 receptors.
TLDR
U-46619 raises blood pressure and releases AVP by activates brain receptors by activating brain receptors in conscious rats and explains approximately one-half of the pressor response.
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