• Corpus ID: 43133845

The effect of propranolol on metabolism and on membrane-associated polysaccharide components of Herpetomonas muscarum muscarum.

  title={The effect of propranolol on metabolism and on membrane-associated polysaccharide components of Herpetomonas muscarum muscarum.},
  author={Angela H. Lopes and Celuta Sales Alviano and Jayme Angluster and Wanderley de Souza and Aron Jurkiewicz},
  journal={Research communications in chemical pathology and pharmacology},
  volume={42 2},
The effects of propranolol on the metabolism (cell growth, cell differentiation and cell respiration) as well as on membrane-associated polysaccharide components of Herpetomonas muscarum muscarum were investigated. At the dose of 10(-2) and 10(-3) mM the drug increased significantly the number of the more differentiated opisthomastigote form of the protozoan, whereas at higher concentrations (10(-1) mM) total inhibition of growth occurred with gross cell lysis. Propranolol (10(-3) mM) enhanced… 
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