The effect of pretreatment or combined treatment of quercetin on menadione toxicity in rat primary mixed glial cells in vitro.

Abstract

Neurons and glia are highly susceptible to reactive oxygen species that play a key role in various neurodegenerative diseases. Menadione, a synthetic derivative of vitamin K, induces reactive oxygen generation. Quercetin one of the most ubiquitous bioflavonoids in food of plant origin, has strong antioxidant activities on different cell types, however… (More)
DOI: 10.1007/s10616-009-9235-7

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