The effect of pregabalin on preoperative anxiety and sedation levels: a dose-ranging study.

@article{White2009TheEO,
  title={The effect of pregabalin on preoperative anxiety and sedation levels: a dose-ranging study.},
  author={Philip Francis White and Burcu Tufanogullari and Jimmie Taylor and Kevin Klein},
  journal={Anesthesia and analgesia},
  year={2009},
  volume={108 4},
  pages={
          1140-5
        }
}
BACKGROUND Pregabalin is a gabapentinoid compound, which has been alleged to possess anxiolytic, analgesic, and anticonvulsant properties. We hypothesized that premedication with oral pregabalin would produce dose-related reductions in acute (state) anxiety and increases in sedation (sleepiness) before induction of general anesthesia. A secondary objective was to determine if premedication with pregabalin would reduce postoperative pain. METHODS One hundred eight ASA I-III outpatients… CONTINUE READING
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