The effect of pre-operative aspirin on bleeding, transfusion, myocardial infarction, and mortality in coronary artery bypass surgery: a systematic review of randomized and observational studies.

@article{Sun2008TheEO,
  title={The effect of pre-operative aspirin on bleeding, transfusion, myocardial infarction, and mortality in coronary artery bypass surgery: a systematic review of randomized and observational studies.},
  author={Jack C. J. Sun and Richard Whitlock and Ji Dong Cheng and John W. Eikelboom and Lehana Thabane and Mark Andrew Crowther and Kevin Hong To Teoh},
  journal={European heart journal},
  year={2008},
  volume={29 8},
  pages={1057-71}
}
AIMS To obtain estimates of the efficacy and safety of pre-operative aspirin in patients undergoing coronary artery bypass grafting (CABG). METHODS AND RESULTS Eligible studies included randomized controlled trials (RCTs) and observational studies of patients undergoing CABG, comparing pre-operative aspirin with no aspirin/placebo, and reporting at least one of our primary outcomes. In eight RCTs (n = 805), pre-operative aspirin increased post-operative bleeding [Mean difference (MD), 104.9… CONTINUE READING

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