The effect of pore size on cell adhesion in collagen-GAG scaffolds.

  title={The effect of pore size on cell adhesion in collagen-GAG scaffolds.},
  author={Fergal J O'Brien and Brendan A C Harley and Ioannis Vassilios Yannas and L. C. Jordan Gibson},
  volume={26 4},
The biological activity of scaffolds used in tissue engineering applications hypothetically depends on the density of available ligands, scaffold sites at which specific cell binding occurs. Ligand density is characterized by the composition of the scaffold, which defines the surface density of ligands, and by the specific surface area of the scaffold, which defines the total surface of the structure exposed to the cells. It has been previously shown that collagen-glycosaminoglycan (CG… CONTINUE READING
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