The effect of perchlorate, thiocyanate, and nitrate on thyroid function in workers exposed to perchlorate long-term.

@article{Braverman2005TheEO,
  title={The effect of perchlorate, thiocyanate, and nitrate on thyroid function in workers exposed to perchlorate long-term.},
  author={Lewis E. Braverman and Xuemei He and Sam Pino and Mary Cross and Barbarajean Magnani and Steven H Lamm and Michael B. Kruse and Arnold Engel and Kenny S. Crump and John P. Gibbs},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2005},
  volume={90 2},
  pages={
          700-6
        }
}
Perchlorate (ClO(4)(-)) and thiocyanate (SCN(-)) are potent and nitrate (NO(3)(-)) a weak competitive inhibitor of the thyroid sodium-iodide symporter. To determine the effects of long-term, high ClO(4)(-) exposure on thyroid function, we conducted a study of 29 workers employed for at least 1.7 yr (50% over 5.9 yr) in an ammonium ClO(4)(-) production plant in Utah. Serum ClO(4)(-), SCN(-), and NO(3)(-); serum T(4), free T(4) index, total T(3), thyroglobulin (Tg), and TSH; 14-h thyroid… CONTINUE READING
44 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 44 extracted citations

Similar Papers

Loading similar papers…