The effect of pentoxifylline on the healing of full-thickness skin defects of diabetic and normal rats

@article{Karasoy2002TheEO,
  title={The effect of pentoxifylline on the healing of full-thickness skin defects of diabetic and normal rats},
  author={Aysin Karasoy and Ismail Kuran and Tahir Turan and S. Hacıkerim and L{\"u}tf{\"u} Baş and Ayşim Sungun},
  journal={European Journal of Plastic Surgery},
  year={2002},
  volume={25},
  pages={253-257}
}
In this paper, the effects of systemic pentoxifylline administration on normal and diabetic wound healing are studied. Twenty-four normoglycemic and 24 diabetic rats were compared, exploring the healing of standardized (15×15 mm) full-thickness wounds by secondary intention. Twelve rats of both groups received intraperitoneal pentoxifylline 10 mg/kg per day. The strength of the healed tissues was evaluated by straining tests, the healing time of each wound was recorded, and the healed tissues… CONTINUE READING

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