The effect of pentobarbital on the electrical activity of LHRH pulse generator in the ovariectomized rat with or without estrogen priming.

Abstract

Effects of pentobarbital sodium (PB) on the electrical activity of LHRH pulse generator were investigated in the ovariectomized (OVX) rat fitted with chronically implanted electrode arrays in the arcuate-median eminence region of the hypothalamus. PB was injected intraperitoneally (i.p.) at a dose of 32 mg/kg bw, which has blocked the surge of LH secretion… (More)

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