The effect of pathogen reduction technology (Mirasol) on platelet quality when treated in additive solution with low plasma carryover.

@article{Johnson2011TheEO,
  title={The effect of pathogen reduction technology (Mirasol) on platelet quality when treated in additive solution with low plasma carryover.},
  author={Lacey Johnson and Kelly M Winter and Samantha Reid and Tanja Hartkopf-Theis and Susanne Marschner and Raymond P Goodrich and Denese C Marks},
  journal={Vox sanguinis},
  year={2011},
  volume={101 3},
  pages={208-14}
}
BACKGROUND AND OBJECTIVES Pathogen reduction technologies (PRT) for platelets are now compatible with both plasma and platelet additive solutions (PAS). The aim of this study was to examine the effect of PRT on the platelet storage lesion, in the presence of PAS with low plasma carryover. MATERIALS AND METHODS PRT-treated (Mirasol) and untreated buffy coat-derived platelet concentrates prepared in 28% plasma/PAS-IIIM were evaluated using in vitro cell quality parameters on days 1, 2, 5, and 7… CONTINUE READING

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