The effect of parathyroid hormone and teriparatide on fracture healing.

  title={The effect of parathyroid hormone and teriparatide on fracture healing.},
  author={Eric J Campbell and Graeme M Campbell and David Arthur Hanley},
  journal={Expert opinion on biological therapy},
  volume={15 1},
INTRODUCTION Daily subcutaneous injections of parathyroid hormone (PTH), and its synthetic peptide fragment, teriparatide (PTH 1-34, TPTD), have a net anabolic effect on bone and prevent osteoporotic fractures. TPTD is currently approved for this indication worldwide. Because of the anabolic effect, there is an interest in a role for TPTD (and, where available, human PTH 1-84) in improving bone healing after a fracture. PTH has been studied in animal fracture healing models and in a limited… CONTINUE READING
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Pharmacologic mechanisms of therapeutics: parathyroid hormone

  • DA Hanley, PM Watson, AB Hodsman, DM. Dempster
  • 3rd Edition. Chapter
  • 2008
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