The effect of oxygen on the development of preimplantation mouse embryos in vitro.

@article{Quinn1978TheEO,
  title={The effect of oxygen on the development of preimplantation mouse embryos in vitro.},
  author={Patrick Quinn and G M Harlow},
  journal={The Journal of experimental zoology},
  year={1978},
  volume={206 1},
  pages={73-80}
}
The optimal oxygen tension for development of preimplantation mouse embryos to the blastocyst stage in vitro was found to be between 2.5% and 5%. One- and two-cell embryos had a more sharply defined range of oxygen tension capable of supporting development than 8-cell and morula stages. At all stages of development, more embryos developed to the blastocyst stage under 5% O2 compared to the numbers of developing under higher oxygen tensions (20% and 40% O2). The blastocysts developing under 20… CONTINUE READING