The effect of ovariectomy combined with hindlimb unloading and reloading on the long bones of mature Sprague-Dawley rats.

@article{Tou2008TheEO,
  title={The effect of ovariectomy combined with hindlimb unloading and reloading on the long bones of mature Sprague-Dawley rats.},
  author={Janet C. L. Tou and Andrea B Foley and Yvonne V. Yuan and Sara Arnaud and Charles E. Wade and Marybeth Brown},
  journal={Menopause},
  year={2008},
  volume={15 3},
  pages={494-502}
}
OBJECTIVE To determine the effect of loss of ovarian function and mechanical loading (ie, inactivity) alone or in combination on bone mass and strength. DESIGN Mature (aged 6 mo) rats were ovariectomized to induce loss of ovarian function and bone. Hindlimb unloading (HLU) was used to determine the effect of mechanical unloading and reloading on bone mass… CONTINUE READING