The effect of osmotic and mechanical pressures on water partitioning in articular cartilage.

@article{Maroudas1991TheEO,
  title={The effect of osmotic and mechanical pressures on water partitioning in articular cartilage.},
  author={Alice Maroudas and E. J. Wachtel and G Grushko and Elton P. Katz and P O Weinberg},
  journal={Biochimica et biophysica acta},
  year={1991},
  volume={1073 2},
  pages={285-94}
}
X-ray diffraction measurements on native and proteoglycan-free articular cartilage have been made in order to test the dependence of the lateral packing of the collagen molecules on the osmotic pressure gradient, either naturally occurring or externally applied, between the intra- and extrafibrillar compartments. From the information on collagen packing we have been able to calculate, albeit with several assumptions, the amount of intrafibrillar water as a function of pressure. In parallel with… CONTINUE READING

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