Corpus ID: 25613846

The effect of ornithine-alpha-ketoglutarate on insulin and glucagon secretion in normal subjects.

@article{Krassowski1981TheEO,
  title={The effect of ornithine-alpha-ketoglutarate on insulin and glucagon secretion in normal subjects.},
  author={Janusz Krassowski and J. Rousselle and Edward Maeder and J. P. Felber},
  journal={Acta endocrinologica},
  year={1981},
  volume={98 2},
  pages={
          252-5
        }
}
  • Janusz Krassowski, J. Rousselle, +1 author J. P. Felber
  • Published 1981
  • Medicine
  • Acta endocrinologica
  • Ornithine-alpha-ketoglutarate (OAK), a drug commonly used in various catabolic states, was studied for its acute effects on endocrine pancreas. A 30-min infusion of OAK (20 g/m2) induced significant increases in insulin levels (from 15 through 60 min) and in glucagon levels (from 15 through 90 min). However, OAK-induced insulin and glucagon responses were lower than after a 0.5 g/kg arginine infusion. The fluctuations of blood glucose levels were much less marked during OAK infusion than during… CONTINUE READING

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