The effect of oral phosphate administration on major indices of skeletal metabolism in normal subjects.

@article{Silverberg1986TheEO,
  title={The effect of oral phosphate administration on major indices of skeletal metabolism in normal subjects.},
  author={Shonni J. Silverberg and Elisabeth Ann Shane and Thomas L. Clemens and David W. Dempster and Gino V. Segre and Robert F. Lindsay and John P. Bilezikian},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1986},
  volume={1 4},
  pages={383-8}
}
The effect of brief periods of phosphate administration on indices of human skeletal metabolism was investigated. Thirteen subjects (8 women, 5 men; 19-36 years old) received 2 g of oral phosphate daily for 5 days. Serum phosphorus rose 26% (3.8 +/- 0.1 mg/dl to 4.8 +/- 0.1 mg/dl; p less than .01) while total calcium fell (9.3 +/- 0.1 mg/dl to 8.9 +/- 0.1 mg/dl; p less than .01). Parathyroid hormone levels increased by 50% (14.1 +/- 2.0 pg/ml to 21.5 +/- 1.7 pg/ml; p less than .05) although… CONTINUE READING
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