The effect of oral antiplatelet agents on tissue plasminogen activator-mediated thrombolysis in a rabbit model of thromboembolic stroke.

Abstract

OBJECTIVE The success of thrombolytic therapy in acute stroke relies on timely reperfusion. The current study examines the efficacy of antiplatelet agents as adjuvants for thrombolytic therapy. METHODS Using an established rabbit model of clot embolization and a randomized blinded design, rabbits (n = 8 in each group) were orally pretreated daily for 5… (More)

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@article{Bednar1996TheEO, title={The effect of oral antiplatelet agents on tissue plasminogen activator-mediated thrombolysis in a rabbit model of thromboembolic stroke.}, author={Martin Bednar and John Quilley and S. R. Russell and Shawna Fuller and C. Booth and D. Howard and Christian Gross}, journal={Neurosurgery}, year={1996}, volume={39 2}, pages={352-9} }