The effect of one prophylactic dosage of antibiotics on experimentally induced lethal intraabdominal sepsis.
@article{Brolin1984TheEO, title={The effect of one prophylactic dosage of antibiotics on experimentally induced lethal intraabdominal sepsis.}, author={J. Brolin and G. Lahnborg and C. Nord}, journal={Acta chirurgica Scandinavica}, year={1984}, volume={150 3}, pages={ 239-44 } }
In order to study the effect of one preoperative dosage of antibiotic on the mortality rate, incidence of abscesses, adhesions and intraperitoneal fluid, a previously described reproducible experimental model of intraabdominal infections in rats has been used. Preoperatively, the rats were fed with lean ground beef for two weeks in order to change the intestinal microflora into a microflora similar to humans. The antibiotics tested were: doxycycline (1 mg), cefoxitin (40 mg), tinidazole (8 mg… CONTINUE READING
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