The effect of oestradiol on vaginal collagen metabolism in postmenopausal women with genuine stress incontinence.

@article{Jackson2002TheEO,
  title={The effect of oestradiol on vaginal collagen metabolism in postmenopausal women with genuine stress incontinence.},
  author={Simon R. Jackson and Mark James and Paul G. Abrams},
  journal={BJOG : an international journal of obstetrics and gynaecology},
  year={2002},
  volume={109 3},
  pages={339-44}
}
OBJECTIVE To determine whether oestrogen replacement will produce an improvement in the quantity, or quality, of pelvic collagen in postmenopausal women. DESIGN A prospective double-blind placebo controlled trial of oestrogen therapy. SETTING Southmead Hospital, Bristol, UK. POPULATION Fifty-five postmenopausal women with a urodynamic diagnosis of genuine urinary stress incontinence. METHODS Randomisation to a six-month, double-blind, placebo-controlled, trial of oestradiol valerate 2mg… CONTINUE READING
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