The effect of normovolemic modified ultrafiltration on inflammatory mediators, endotoxins, terminal complement complexes and clinical outcome in high-risk cardiac surgery patients.

@article{Papadopoulos2013TheEO,
  title={The effect of normovolemic modified ultrafiltration on inflammatory mediators, endotoxins, terminal complement complexes and clinical outcome in high-risk cardiac surgery patients.},
  author={Nestoras Papadopoulos and Fahrad Bakhtiary and Verena Gr{\"u}n and Christian Friedrich Weber and Christian Stra\sser and Anton Moritz},
  journal={Perfusion},
  year={2013},
  volume={28 4},
  pages={306-14}
}
OBJECTIVE The clinical benefit of normovolemic modified ultrafiltration (N-MUF) after cardiac surgery is still debated. As we have shown in a previous publication, there is a significant improvement in platelet function, so we were interested in whether ultrafiltration can reduce plasma levels of endotoxins, terminal complement complexes and cytokines after cardiopulmonary bypass (CPB) in adults with increased risk profiles. METHODS In this single-center, prospective, randomized trial, fifty… CONTINUE READING
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