The effect of non-coding DNA variations on P53 and cMYC competitive inhibition at cis-overlapping motifs.


Non-coding DNA variations play a critical role in increasing the risk for development of common complex diseases, and account for the majority of SNPs highly associated with cancer. However, it remains a challenge to identify etiologic variants and to predict their pathological effects on target gene expression for clinical purposes. Cis-overlapping motifs… (More)
DOI: 10.1093/hmg/ddw030


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