The effect of nitrofurazone on the thiamin status of chickens.

@article{Ali1983TheEO,
  title={The effect of nitrofurazone on the thiamin status of chickens.},
  author={Badreldin H. Ali},
  journal={Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology},
  year={1983},
  volume={76 1},
  pages={
          131-4
        }
}
  • B. Ali
  • Published 1983
  • Biology, Medicine
  • Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology
Nitrofurazone, given orally at doses of 10 and 20 mg/kg for seven days, decreased the activity of erythrocyte transketolase (TK) and increased the activation of TK by thiamin pyrophosphate (TPP effect %). Nitrofurazone also decreased the feed intake and growth of the chickens, and increased the concentrations of lactate and pyruvate of their blood. It was concluded that nitrofurazone has induced thiamin deficiency in the treated birds. Pair-feeding experiments showed that the decreased growth… 
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It is found that ethanol treatment has an adverse effect on the thiamin status of the turkey poult, a new animal model for alcohol-induced cardiomyopathy in humans.

References

SHOWING 1-10 OF 11 REFERENCES
The effect of thiamine deficiency on the glucose oxidative pathway of rat erythrocytes.
TLDR
The data to be presented demonstrate that rat erythrocyte transketolase activity is reduced by the removal of thiamine from the diet, which lends further support to the argument that methylene blue activates the glucose oxidative pathway in ERYthrocytes.
Establishment of the toxic level of nitrofurazone for young liquid-fed calves.
TLDR
Thiamine supplementation had no effect on the onset of nervous signs or on growth rate and milk replacer intake and plasma glucose, lactate, pyruvate, and magnesium appeared generally unrelated to the drug effects.
An Investigation of the Morphological Changes in Young Chickens and the Reproductive Performance of Adult Chickens Fed Furazolidone or Nitrofurazone
TLDR
The poultryman is faced with a never-ending list of drugs that are placed at his disposal for treating or preventing various poultry diseases, and few studies are conducted to evaluate drugs for other properties.
Nitrofurazone dermatitis following coitus.
  • C. George
  • Medicine
    Journal of the American Medical Association
  • 1954
TLDR
The following case is reported as being of particular interest because of the rather unusual mode of accidental contact to the drug.
Thiamine status in alcoholism.
TLDR
It was concluded that the TPP effect was frequently misleading in subjects with gross thiamine deficiency (Wernicke'S encephalopathy) and it was suggested that erythrocyte transketolase activity may be the best parameter to use in assessingThiamine status with the erythroc yte apotransketolases assay.
INHIBITION OF SPERMATOGENESIS AND ATROPHY OF THE TESTIS CAUSED BY NITROFURAN COMPOUNDS
1. Cytotoxic effects on the testis of 5‐nitro‐2‐furaldehyde acetylhydrazone, 5‐(5‐nitro‐2‐furyl)‐l, 3, 4‐oxadiazoIine‐2‐one, N‐(5‐nitro‐2‐furfurylidene)‐3‐aminooxazoline‐2‐one and
The Effect of Nitrofurazone on the Endocrine, Secretory and Spermatogenic Functions of the Rat Testis
Der Einfluß von Nitrofurazon auf die endokrine, sekretorische und spermatogenetische Funktion des Rattenhodens
Rapid enzymatic measurement of blood lactate and pyruvate. Use and significance of metaphosphoric acid as a common precipitant.
TLDR
The method is especially valuable in the emergent clinical situation in which measurements of lactate and pyruvate are obtained for assessment of the severity of shock and other forms of cardiorespiratory failure.
Biochemical changes in thiamine deficiencies.
  • C. Gubler
  • Medicine
    Journal of nutritional science and vitaminology
  • 1976
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