The effect of nitrate supplementation on exercise performance in healthy individuals: a systematic review and meta-analysis.

  title={The effect of nitrate supplementation on exercise performance in healthy individuals: a systematic review and meta-analysis.},
  author={Matthew W Hoon and Nathan A. Johnson and Phillip G. Chapman and Louise M. Burke},
  journal={International journal of sport nutrition and exercise metabolism},
  volume={23 5},
  • M. Hoon, N. Johnson, L. Burke
  • Published 1 October 2013
  • Medicine
  • International journal of sport nutrition and exercise metabolism
The purpose of this review was to examine the effect of nitrate supplementation on exercise performance by systematic review and meta-analysis of controlled human studies. A search of four electronic databases and cross-referencing found 17 studies investigating the effect of inorganic nitrate supplementation on exercise performance that met the inclusion criteria. Beetroot juice and sodium nitrate were the most common supplements, with doses ranging from 300 to 600 mg nitrate and prescribed in… 

Figures from this paper

The Effect of Nitrate Supplementation on Exercise Tolerance and Performance: A Systematic Review and Meta-Analysis

Nitrate supplementation is likely to improve exercise tolerance and capacity that may improve exercise performance and more research is required to determine the optimal dose and duration of nitrate supplementation.

Ergogenic Effect of Nitrate Supplementation: A Systematic Review and Meta-analysis

Supplemental digital content is available in the text. ABSTRACT Although over 100 studies and reviews have examined the ergogenic effects of dietary nitrate (NO3−) supplementation in young, healthy

The Effect of Dietary Nitrate Supplementation on Endurance Exercise Performance in Healthy Adults: A Systematic Review and Meta-Analysis

Dietary NO3− supplementation is likely to elicit a positive outcome when testing endurance exercise capacity, whereas dietary NO3 − supplementation is less likely to be effective for time-trial performance.

Effects of Nitrate Supplementation on Exercise Performance in Humans: A Narrative Review

The current recommendation of nitrate supplementation is discussed, as well as possible health complications associated with nitrate intake for athletes, and dietary strategies of covering nitrate needs through sufficient intake of nitrates-rich foods alone are presented.

Effect of dietary nitrate on human muscle power: a systematic review and individual participant data meta-analysis

Acute or chronic dietary NO 3 − intake significantly increases maximal muscle power in humans and the magnitude of this effect–on average, ~ 5%–is likely to be of considerable practical and clinical importance.

Effects of Dietary Nitrates on Time Trial Performance in Athletes with Different Training Status: Systematic Review

There might be a fibre-type specific role in nitric oxide production and, therefore, supplement of ergogenicity in time trial performance after increased dietary nitrate intake, according to VO2max and recent histological observations of muscle fibres.

The effect of nitrate supplementation on muscle contraction in healthy adults

It is suggested that four days of supplementation elicits peripheral responses in muscle that attenuate muscular fatigue during exhaustive exercise under hypovolemic conditions.

Effects of a Short-Term High-Nitrate Diet on Exercise Performance

It is suggested that a high-nitrate diet could be a feasible and effective strategy to improve exercise performance and should be considered as a viable and effective nutritional intervention.

Influence of dietary nitrate on the physiological determinants of exercise performance: a critical review.

  • Andrew M. Jones
  • Education
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme
  • 2014
A "state-of-the-art" review of the literature pertinent to the evaluation of the efficacy of nitrate supplementation in altering the physiological determinants of sport and exercise performance is provided.



Carbohydrate ingestion during endurance exercise improves performance in adults.

The data support that ingestion of CHO between 30 and 80 g/h enhances endurance exercise performance in adults, and the weighted mean improvement in exercise performance favored CHO ingestion.

Acute dietary nitrate supplementation improves cycling time trial performance.

It is suggested that acute dietary nitrate supplementation with 0.5 L of BR improves cycling economy, as demonstrated by a higher PO for the same VO2 and enhances both 4- and 16.1-km cycling TT performance.

Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise.

It is indicated that dietary NO(3)(-) supplementation acutely reduces BP and the O(2) cost of submaximal exercise and that these effects are maintained for at least 15 days if supplementation is continued.

Sodium nitrate supplementation does not enhance performance of endurance athletes.

Sodium nitrate supplementation did not improve a 40-min distance-trial performance in endurance athletes and concentration of plasma ET-1 increased significantly after exercise after supplementation with sodium nitrate.

Influence of acute dietary nitrate supplementation on 50 mile time trial performance in well-trained cyclists

Dietary nitrate supplementation has been reported to improve short distance time trial (TT) performance by 1–3 % in club-level cyclists. It is not known if these ergogenic effects persist in longer

Nitrate supplementation's improvement of 10-km time-trial performance in trained cyclists.

Six days of nitrate supplementation reduced VO₂ during submaximal exercise and improved time-trial performance in trained cyclists.

Dietary nitrate supplementation improves rowing performance in well-trained rowers.

Conclusively, nitrate supplementation in the form of BR juice resulted in improved maximal rowing-ergometer repetitions, particularly in the later stages of exercise.

Whole beetroot consumption acutely improves running performance.

Dietary nitrate does not enhance running performance in elite cross-country skiers.

Acute ingestion of dietary nitrate may not represent an effective strategy for reducing the oxygen cost of submaximal exercise or for enhancing endurance exercise performance in highly trained cross-country skiers.

Acute administration of inorganic nitrate reduces VO(2peak) in endurance athletes.

A single oral dose of inorganic nitrate acutely reduces VO(2peak) without compromising the maximal exercise performance and enhances the tolerance of endurance athletes to high intensity exercise.