The effect of nicotine on sign-tracking and goal-tracking in a Pavlovian conditioned approach paradigm in rats

@article{Palmatier2012TheEO,
  title={The effect of nicotine on sign-tracking and goal-tracking in a Pavlovian conditioned approach paradigm in rats},
  author={Matthew I. Palmatier and Kimberley R. Marks and S. A. Jones and Kyle S. Freeman and Kevin M. Wissman and Ashley Brianna Sheppard},
  journal={Psychopharmacology},
  year={2012},
  volume={226},
  pages={247-259}
}
Nicotine (NIC) potently increases operant responding for non-NIC reinforcers, and this effect may depend on drug-mediated increases in incentive motivation. According to this hypothesis, NIC should also potently increase approach to Pavlovian-conditioned stimuli associated with rewards. The present studies explored the effects of NIC on Pavlovian-conditioned approach responses. To do so, liquid dippers were used to deliver an unconditioned stimulus (US; 0.1 ml sucrose) after presentation of a… CONTINUE READING
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