The effect of nicotine on reproduction and attachment of human gingival fibroblasts in vitro.

@article{Peacock1993TheEO,
  title={The effect of nicotine on reproduction and attachment of human gingival fibroblasts in vitro.},
  author={Mark E. Peacock and David E. Sutherland and George S. Schuster and William A Brennan and Robert B O'Neal and Stephen Strong and Thomas E Van Dyke},
  journal={Journal of periodontology},
  year={1993},
  volume={64 7},
  pages={658-65}
}
The ability of fibroblasts to reproduce and attach to teeth is of paramount importance in re-establishing the lost connective tissue attachment after periodontal therapy. This study examined the effect of nicotine, a major component of the particulate phase of tobacco smoke, on human gingival fibroblast (HGF) reproduction and attachment to tissue culture surfaces. Pooled HGF cultures made from explants of gingival biopsies were utilized between passages 5 and 10 and plated in 96-well plates at… CONTINUE READING
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