The effect of niaprazine on some common sleep disorders in children

@article{Ottaviano2004TheEO,
  title={The effect of niaprazine on some common sleep disorders in children},
  author={Salvatore Ottaviano and Flavia Giannotti and Flavia Cortesi},
  journal={Child's Nervous System},
  year={2004},
  volume={7},
  pages={332-335}
}
A placebo-controlled double-blind clinical trial on the effect of niaprazine on children with some common sleep disorders was carried out. Niaprazine at a daily dosage of 1 mg/kg body weight or placebo at random was administered to a selected group of 36 children (aged from 6 months to 6 years) suffering from frequent nighttime waking or inability to fall asleep. The effect of niaprazine (or placebo) on sleep disorders was studied by means of continuous home-videorecorded sleep before and after… 
View on Springer
ncbi.nlm.nih.gov
19 Citations
Background Citations
2
Methods Citations
1

19 Citations

Citation Type

Citation Type

Overview of current management of sleep disturbances in children: I—Pharmacotherapy
Practitioner Review: Treatment of chronic insomnia in children and adolescents with neurodevelopmental disabilities
TLDR
A tentative guide for the use of drugs for insomnia in children with NDDs is provided and well-controlled studies employing both objective polysomnography and subjective sleep measures are needed to determine the efficacy, effectiveness, and safety of the currently prescribed pediatric sleep medicines.
Pharmacological treatment of sleep disturbance in developmental disabilities: a review of the literature.
Pediatric insomnia: Treatment
TLDR
This article focuses on psychotherapeutic and psychopharmacologic interventions for youth with insomnia, and describes an effective approach to consultation with pediatric behavioral sleep medicine specialists.
Pharmacotherapeutic management of sleep disorders in children with neurodevelopmental disorders
TLDR
This narrative review, the authors highlight and summarize the most common drugs and supplements used for the treatment of sleep problems in children with neurodevelopmental disabilities and recommend the use of melatonin and melatonin receptor agonists, sedating antidepressants, antipsychotics, antihistamines, gabapentin, clonidine and orexin receptor antagonists, and benzodiazepines and hypnotic Benzodiazepine receptor agonist.
Sleeping without Prescription: Management of Sleep Disorders in Children with Autism with Non-Pharmacological Interventions and Over-the-Counter Treatments
TLDR
A narrative review of the literature, presenting the available evidence on the following treatments: sleep education, behavioral interventions, complementary and alternative medicine, and commonly used over-the-counter medications and supplements.
The trial of infant response to diphenhydramine: the TIRED study--a randomized, controlled, patient-oriented trial.
TLDR
During 1 week of therapy and at follow-up 2 and 4 weeks later, diphenhydramine was no more effective than placebo in reducing nighttime awakening or improving overall parental happiness with sleep for infants.
Clinically Oriented Subtyping of Chronic Insomnia of Childhood
Pediatric insomnia: new insights in clinical assessment and treatment options.
TLDR
A new classification of pediatric insomnia is proposed, based on both genetic and clinical aspects, and specific treatment options, including sleep hygiene, behavioral strategies and pharmacological treatment are suggested.
Le traitement pharmacologique de l’insomnie en pédopsychiatrie
TLDR
Pharmacological treatment of insomnia should be considered in patients with attention deficit hyperactivity disorder in which sleep disturbances can be aggravated by psycho stimulant treatment, in autism spectrum disorders, and in the anxiety/depression.
...
...

References

SHOWING 1-10 OF 29 REFERENCES
Controlled trial of trimeprazine tartrate for night waking.
TLDR
The results are consistent with the idea that trimeprazine tartrate may be a useful short term treatment for night waking in young children.
The sleepless child.
TLDR
The sleepless child is a frequent concern in pediatric office visits and the clinical presentation, evaluation, and treatment options are described, which include clinical history and may include diagnostic tests specific to possible diagnoses.
Behavioral Treatment of Multiple Childhood Sleep Disorders
TLDR
“graduated extinction” (gradually increasing the time before attending to the child's crying) resulted in rapid reductions in these sleep disorders and data on parental depression and marital satisfaction showed general improvement as a function of improved child sleep patterns.
Night Waking in Infants During the First 14 Months
  • J. Bernal
  • Medicine
    Developmental medicine and child neurology
  • 1973
TLDR
The rôle of parental handling in the development of sleep problems is discussed; while there was no pattern of care common to all mothers of the problem infants, the majority were very responsive.
Sleep disturbance in the young child.
  • M. Bax
  • Psychology
    British medical journal
  • 1980
Parents report two common problems about their child's sleep in the early years of life. The first is difficulty in getting the child to go to bed, although subsequently he sleeps on through the…
Sleep problems in early childhood: continuities, predictive factors, and behavioral correlates.
A longitudinal study, based on interviews with 308 middle-class, preponderantly white mothers, provided an opportunity to evaluate the continuity, predictive factors, and behavioral correlates of…
Niaprazine, a selective brain catecholamine depletor
Sleep and its Disorders in Children
TLDR
This book will raise the expectations of patients as to what they may expect of DAVID BATES their "specialist" doctors and the paramedical departments and will help to banish finally the notion that any neuromuscular disease is untreatable.
The effect of niaprazine on the turnover of 5-hydroxytryptamine in the rat brain
Home-recorded sleep in 2- and 9-month-old infants.
  • T. Anders
  • Psychology, Medicine
    Journal of the American Academy of Child Psychiatry
  • 1978
...
...