The effect of neuronal expression of heat shock proteins 26 and 27 on lifespan, neurodegeneration, and apoptosis in Drosophila.

@article{Liao2008TheEO,
  title={The effect of neuronal expression of heat shock proteins 26 and 27 on lifespan, neurodegeneration, and apoptosis in Drosophila.},
  author={Pin-Chao Liao and Hung-Yu Lin and Chiou-Hwa Yuh and Lin-Kwei Yu and H Wang},
  journal={Biochemical and biophysical research communications},
  year={2008},
  volume={376 4},
  pages={637-41}
}
Heat shock proteins (Hsps) are chaperones thought to increase lifespan, enhance stress resistance, and prevent apoptosis and neurodegenerative diseases. Our previous study reported that ubiquitous expression of hsp26 or hsp27 extended Drosophila lifespan. The effect of neuronal expression of hsp26 and hsp27 in Drosophila on the above-mentioned functions has not yet been investigated. Here, we show that neuronal expression of hsp26 or hsp27 improved lifespan and increased resistance to oxidative… CONTINUE READING

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References

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Showing 1-10 of 49 references

Z

A. Chaudhuri, K. Bowling, C. Funderburk, H. Lawal, A. Inamdar
Wang, J.M. O’Donnell, Interaction of genetic and environmental factors in a Drosophila parkinsonism model, J. Neurosci. 27 • 2007
View 4 Excerpts
Highly Influenced

Interaction of genetic and environmental factors in a Drosophila parkinsonism model.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2007

J

A. Zourlidou, T. Gidalevitz, +4 authors D. S. Latchman
de Belleroche, S.J. Tabrizi, R.I. Morimoto, G.P. Bates, Hsp27 overexpression in the R6/2 mouse model of Huntington’s disease: chronic neurodegeneration does not induce Hsp27 activation, Hum. Mol. Genet. 16 • 2007
View 2 Excerpts

Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease.

Molecular therapy : the journal of the American Society of Gene Therapy • 2007
View 2 Excerpts

Trinucleotide repeat disorders.

Annual review of neuroscience • 2007
View 1 Excerpt

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