The effect of nasally administered budesonide respules on adrenal cortex function in patients with chronic rhinosinusitis.

@article{Sachanandani2009TheEO,
  title={The effect of nasally administered budesonide respules on adrenal cortex function in patients with chronic rhinosinusitis.},
  author={Neil S. Sachanandani and Jay F. Piccirillo and Maggie A Kramper and Stanley E. Thawley and Anna Vlahiotis},
  journal={Archives of otolaryngology--head & neck surgery},
  year={2009},
  volume={135 3},
  pages={303-7}
}
OBJECTIVES To evaluate whether nasal administration of budesonide in adults with chronic rhinosinusitis for 30 days suppresses adrenal function and to assess its clinical efficacy. DESIGN An open-label prospective study. SETTING Academic medical center. PATIENTS We assessed adrenal function in 9 patients using the cosyntropin test before and after budesonide therapy. INTERVENTION Budesonide respule therapy. MAIN OUTCOME MEASURE Scores from the Sino-Nasal Outcome Test-20 (SNOT-20), a… CONTINUE READING