The effect of myostatin on proliferation and lipid accumulation in 3T3-L1 preadipocytes.

@article{Zhu2015TheEO,
  title={The effect of myostatin on proliferation and lipid accumulation in 3T3-L1 preadipocytes.},
  author={Hui Juan Zhu and Hui Pan and Xu Zhang and Nai shi Li and Lin Wang and Hong Yang and Feng-ying Gong},
  journal={Journal of molecular endocrinology},
  year={2015},
  volume={54 3},
  pages={217-26}
}
Myostatin is a critical negative regulator of skeletal muscle development, and has been reported to be involved in the progression of obesity and diabetes. In the present study, we explored the effects of myostatin on the proliferation and differentiation of 3T3-L1 preadipocytes by using 3-[4,5-dimethylthiazol-2-yl] 2,5-diphenyl tetrazolium bromide spectrophotometry, intracellular triglyceride (TG) assays, and real-time quantitative RT-PCR methods. The results indicated that recombinant… CONTINUE READING
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