The effect of mutation at M307 in FUT1 gene on susceptibility of Escherichia coli F18 and gene expression in Sutai piglets

@article{Bao2011TheEO,
  title={The effect of mutation at M307 in FUT1 gene on susceptibility of Escherichia coli F18 and gene expression in Sutai piglets},
  author={Wen-bin Bao and Lan Ye and Zhang-yuan Pan and Jing li Zhu and Zi-Dong Du and Guo-Qiang Zhu and Xue-gen Huang and Sheng-long Wu},
  journal={Molecular Biology Reports},
  year={2011},
  volume={39},
  pages={3131-3136}
}
Escherichia coli F18 (ECF18) is a common porcine enteric pathogen. The pathogenicity of ECF18 bacteria depends on the existence of ECF18 receptor in the brush border membranes of piglet’s small intestinal mucosa. Alpha (1) fucosyltransferase gene (FUT1) has been identified as the candidate gene controlling the adhesion to ECF18 receptor. The genetic variations in the position of M307 nucleotide in open reading frame of FUT1 have been proposed as a marker for selecting resistant pigs. The… CONTINUE READING