The effect of muscle paralysis using Botox on the healing of tendon to bone in a rat model.

@article{Hettrich2011TheEO,
  title={The effect of muscle paralysis using Botox on the healing of tendon to bone in a rat model.},
  author={Carolyn M. Hettrich and Scott Alan Rodeo and Jo Ann Hannafin and John R. Ehteshami and Beth E. Shubin Stein},
  journal={Journal of shoulder and elbow surgery},
  year={2011},
  volume={20 5},
  pages={688-97}
}
HYPOTHESIS Despite good clinical results after rotator cuff repair, follow-up studies show significant rates of failed healing. This may be because of excessive tension on the repaired tendon due to shoulder motion. We hypothesized that botulinum toxin A injections would result in improved attachment strength and collagen organization at the tendon-bone interface at early time points but may result in decreased mechanical properties at later time points because of the negative effects of stress… CONTINUE READING
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