The effect of mixing lidocaine with propofol on the dose of propofol required for induction of anesthesia.

@article{Tan2003TheEO,
  title={The effect of mixing lidocaine with propofol on the dose of propofol required for induction of anesthesia.},
  author={L Tan and Nian-Chih Hwang},
  journal={Anesthesia and analgesia},
  year={2003},
  volume={97 2},
  pages={461-4, table of contents}
}
UNLABELLED Lidocaine is used to reduce pain associated with propofol injection, either mixed with propofol or preceding it as a separate injection. The addition of lidocaine to propofol causes destabilization of the emulsion and reduces anesthetic potency in rats and humans. We conducted a randomized double-blinded study on 67 patients to assess the effect of mixing lidocaine with propofol on the dose of propofol required for the induction of anesthesia. Patients in Group S (n = 32) received IV… CONTINUE READING
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