The effect of methylphenidate on prefrontal cognitive functioning, inattention, and hyperactivity in velocardiofacial syndrome.

@article{Green2011TheEO,
  title={The effect of methylphenidate on prefrontal cognitive functioning, inattention, and hyperactivity in velocardiofacial syndrome.},
  author={Tamar Green and Ronnie Weinberger and Adele Diamond and Michael Berant and Leora Hirschfeld and A. W. Frisch and Omer Zarchi and Abraham Weizman and Doron Gothelf},
  journal={Journal of child and adolescent psychopharmacology},
  year={2011},
  volume={21 6},
  pages={589-95}
}
OBJECTIVE Methylphenidate (MPH) is commonly used to treat attention-deficit/hyperactivity disorder (ADHD) in all children, including those with velocardiofacial syndrome (VCFS). Yet concerns have been raised regarding its safety and efficacy in VCFS. The goal of this study was to examine the safety and efficacy of MPH in children with VCFS. METHODS Thirty-four children and adolescents with VCFS and ADHD participated in a randomized, controlled trial with a 2:1 ratio of MPH versus placebo. All… CONTINUE READING

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