The effect of metformin on liver blood flow in vivo in normal subjects and patients with non insulin dependent diabetes.

@article{Signore1996TheEO,
  title={The effect of metformin on liver blood flow in vivo in normal subjects and patients with non insulin dependent diabetes.},
  author={A Signore and Vincenzo Fiore and Marco Chianelli and Enrica Procaccini and Raffaella Barone and Giuseppe Ronga and Michael Negri and Paolo Pozzilli},
  journal={Diabetes research and clinical practice},
  year={1996},
  volume={33 2},
  pages={83-7}
}
We previously reported that metformin improves insulin-mediated glucose liver metabolism in patients with non insulin dependent diabetes (NIDDM). It is not clear whether this is a direct effect of metformin on liver metabolism or mediated by other mechanisms such as increased liver blood flow. In this respect it has recently been reported that metformin… CONTINUE READING