The effect of metal attachment to human apotransferrin on its binding to reticulocytes.

@article{Kornfeld1969TheEO,
  title={The effect of metal attachment to human apotransferrin on its binding to reticulocytes.},
  author={Stuart Kornfeld},
  journal={Biochimica et biophysica acta},
  year={1969},
  volume={194 1},
  pages={
          25-33
        }
}
Abstract The effect that metal attachment to apotransferrin exerts on the binding affinity of reticulocyte surface receptors sites for transferrin has been studied using two methods: (1) by direct binding studies using iodinated transferrin and (2) by competition experiments in which the ability of the test transferrin to impair reticulocyte Fe 3+ uptake from 59 Fe 3+ -transferrin was determined. While the absolute values for the dissociation constants for transferrin binding to reticulocytes… CONTINUE READING