The effect of membrane potential on the protonophoric action of oleic acid.

Abstract

Free fatty acids, such as oleic acid, are able to act as uncouplers of oxidative phosphorylation in mitochondria [l]. They can also transport cations across membranes and may have a physiological role in iron transport in the gut [2]. We have previously shown that oleic acid can act as a K+/H+ ion exchange carrier in liposomes [3]. It was proposed that… (More)

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