The effect of meloxicam, a selective COX-2 inhibitor, on the microvasculature of small metastatic liver tumors in rats.

@article{Iwase2007TheEO,
  title={The effect of meloxicam, a selective COX-2 inhibitor, on the microvasculature of small metastatic liver tumors in rats.},
  author={Naoko Iwase and Tetsuro Higuchi and Tsuyoshi Gonda and Hirotoshi Kobayashi and Hiroyuki Uetake and Masayuki Enomoto and Kenichi Sugihara},
  journal={Japanese journal of clinical oncology},
  year={2007},
  volume={37 9},
  pages={
          673-8
        }
}
BACKGROUND COX-2 is involved in tumor angiogenesis and modulation of the production of angiogenetic factors by colorectal carcinoma cells. It has been shown that COX-2 inhibitors have inhibitory activities against various types of tumor, including colorectal carcinoma. In this study, we investigated the tumor vessels of small metastatic liver tumors in rats and the effect of meloxicam, a selective COX-2 inhibitor, on their growth and microvasculature. METHODS The metastatic liver tumors were… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 52 REFERENCES

Involvement of liver-associated immunity in hepatic metastasis formation.

  • The Journal of surgical research
  • 1998
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Cyclooxygenase-2 Expression in Colorectal Adenomas

  • Diseases of the colon and rectum
  • 2003
VIEW 1 EXCERPT