The effect of melatonin on sedation of children undergoing magnetic resonance imaging.

@article{Sury2006TheEO,
  title={The effect of melatonin on sedation of children undergoing magnetic resonance imaging.},
  author={Michael R J Sury and Kelly A Fairweather},
  journal={British journal of anaesthesia},
  year={2006},
  volume={97 2},
  pages={220-5}
}
BACKGROUND Melatonin may induce a natural sleepiness and improve predictability of sedation drugs. We have investigated its clinical value in children sedated for magnetic resonance imaging. METHODS In a stratified randomized double-blind study, 98 children received either melatonin or placebo 10 min before they were sedated with a standard oral regimen. Children >5 and <15 kg received chloral hydrate and those >or=15 and <40 kg had a combination of temazepam with droperidol (T&D). The doses… CONTINUE READING

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