The effect of macrophage activation state on antigen presenting capability as defined by helper T-cell function.


Resident peritoneal cells were obtained from BALB/c mice and enriched for cells of the macrophage lineage by adherence onto 96 well tissue culture plates. Adherent cells were then exposed to various recombinant cytokines or supernatants from cell cultures, for 24 h. The ability of such adherent antigen presenting cells (APC) to support proliferation and… (More)


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