The effect of macrolides on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts.


BACKGROUND Macrolides are known to have anti-inflammatory, immunomodulatory, and tissue reparative effects. The purpose of this study was to determine the effect of macrolides (erythromycin [EM] and roxithromycin [RXM]) on the differentiation of fibroblasts into myofibroblasts and extracellular matrix accumulation in transforming growth factor (TGF) beta1… (More)
DOI: 10.2500/ajra.2010.24.3520


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